2TPL

TYROSINE PHENOL-LYASE FROM CITROBACTER INTERMEDIUS COMPLEX WITH 3-(4'-HYDROXYPHENYL)PROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE AND CS+ ION

2TPL の概要

• エントリーDOI: 10.2210/pdb2tpl/pdb
• 分子名称: TYROSINE PHENOL-LYASE, CESIUM ION, HYDROXYPHENYL PROPIONIC ACID, ... (4 entities in total)
• 機能のキーワード: lyase, plp-dependent enzyme, pyridoxal phosphate
• 由来する生物種: Citrobacter freundii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103905.73

構造登録者

Antson, A.A.,Demidkina, T.V.,Wilson, K.S. (登録日: 1997-01-23, 公開日: 1997-04-01, 最終更新日: 2024-04-03)

• 主引用文献: Sundararaju, B.,Antson, A.A.,Phillips, R.S.,Demidkina, T.V.,Barbolina, M.V.,Gollnick, P.,Dodson, G.G.,Wilson, K.S.; The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.; Biochemistry, 36:6502-6510, 1997; PubMed: 9174368; DOI: 10.1021/bi962917+

実験手法

X-RAY DIFFRACTION (2.5 Å)