2TMN

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN

Summary for 2TMN

Entry DOI	10.2210/pdb2tmn/pdb
Descriptor	Thermolysin, CALCIUM ION, ZINC ION, ... (5 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, metalloproteinase, hydrolase/hydrolase inhibitor
Biological source	Bacillus thermoproteolyticus
Cellular location	Secreted: P00800
Total number of polymer chains	1
Total formula weight	34798.19
Authors	Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (deposition date: 1987-06-29, release date: 1989-01-09, Last modification date: 2022-11-23)
Primary citation	Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157:261-268, 1986 Cited by PubMed: 3709536 DOI: 10.1111/j.1432-1033.1986.tb09664.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation