2RSK

RNA aptamer against prion protein in complex with the partial binding peptide

2RSK の概要

• エントリーDOI: 10.2210/pdb2rsk/pdb
• 分子名称: RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'), partial binding peptide of Major prion protein (2 entities in total)
• 機能のキーワード: aptamer, prion, rna, alzheimer's disease, membrane protein-rna complex, membrane protein/rna
• 由来する生物種: Bos taurus (Bovine)
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P10279
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 10842.15

構造登録者

Mashima, T.,Nishikawa, F.,Kamatari, Y.O.,Fujiwara, H.,Nishikawa, S.,Kuwata, K.,Katahira, M. (登録日: 2012-03-08, 公開日: 2013-02-13, 最終更新日: 2024-05-15)

• 主引用文献: Mashima, T.,Nishikawa, F.,Kamatari, Y.O.,Fujiwara, H.,Saimura, M.,Nagata, T.,Kodaki, T.,Nishikawa, S.,Kuwata, K.,Katahira, M.; Anti-prion activity of an RNA aptamer and its structural basis; Nucleic Acids Res., 41:1355-1362, 2013; PubMed: 23180780; DOI: 10.1093/nar/gks1132

実験手法

SOLUTION NMR