2RSE

NMR structure of FKBP12-mTOR FRB domain-rapamycin complex structure determined based on PCS

2RSE の概要

• エントリーDOI: 10.2210/pdb2rse/pdb
• NMR情報: BMRB: 11471
• 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A, Serine/threonine-protein kinase mTOR, TERBIUM(III) ION (3 entities in total)
• 機能のキーワード: fkbp12, rapamycin, fk506, lanthanide, pcs, isomerase-transferase complex, isomerase/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P62942; Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23486.29

構造登録者

Kobashigawa, Y.,Ushio, M.,Saio, T.,Inagaki, F. (登録日: 2012-01-25, 公開日: 2012-05-30, 最終更新日: 2024-05-15)

• 主引用文献: Kobashigawa, Y.,Saio, T.,Ushio, M.,Sekiguchi, M.,Yokochi, M.,Ogura, K.,Inagaki, F.; Convenient method for resolving degeneracies due to symmetry of the magnetic susceptibility tensor and its application to pseudo contact shift-based protein-protein complex structure determination.; J.Biomol.Nmr, 53:53-63, 2012; PubMed: 22487935; DOI: 10.1007/s10858-012-9623-8

実験手法

SOLUTION NMR