2ROK

Solution structure of the cap-binding domain of PARN complexed with the cap analog

Summary for 2ROK

• Entry DOI: 10.2210/pdb2rok/pdb
• Related: 1WHV
• Descriptor: poly(A)-specific ribonuclease, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: rrm, rbd, cap, structural genomics, rna binding protein, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 1
• Total formula weight: 11835.63

Authors

Nagata, T.,Suzuki, S.,Endo, R.,Shirouzu, M.,Terada, T.,Inoue, M.,Kigawa, T.,Guntert, P.,Hayashizaki, Y.,Muto, Y.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-03-28, release date: 2009-02-10, Last modification date: 2022-03-16)

• Primary citation: Nagata, T.,Suzuki, S.,Endo, R.,Shirouzu, M.,Terada, T.,Inoue, M.,Kigawa, T.,Kobayashi, N.,Guntert, P.,Tanaka, A.,Hayashizaki, Y.,Muto, Y.,Yokoyama, S.; The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition.; Nucleic Acids Res., 36:4754-4767, 2008; PubMed: 18641416; DOI: 10.1093/nar/gkn458

Experimental method

SOLUTION NMR