2ROK

Solution structure of the cap-binding domain of PARN complexed with the cap analog

2ROK の概要

• エントリーDOI: 10.2210/pdb2rok/pdb
• 関連するPDBエントリー: 1WHV
• 分子名称: poly(A)-specific ribonuclease, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• 機能のキーワード: rrm, rbd, cap, structural genomics, rna binding protein, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11835.63

構造登録者

Nagata, T.,Suzuki, S.,Endo, R.,Shirouzu, M.,Terada, T.,Inoue, M.,Kigawa, T.,Guntert, P.,Hayashizaki, Y.,Muto, Y.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2008-03-28, 公開日: 2009-02-10, 最終更新日: 2022-03-16)

• 主引用文献: Nagata, T.,Suzuki, S.,Endo, R.,Shirouzu, M.,Terada, T.,Inoue, M.,Kigawa, T.,Kobayashi, N.,Guntert, P.,Tanaka, A.,Hayashizaki, Y.,Muto, Y.,Yokoyama, S.; The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition.; Nucleic Acids Res., 36:4754-4767, 2008; PubMed: 18641416; DOI: 10.1093/nar/gkn458

実験手法

SOLUTION NMR