2RN5
Humal Insulin Mutant B31Lys-B32Arg
Summary for 2RN5
Entry DOI | 10.2210/pdb2rn5/pdb |
NMR Information | BMRB: 11016 |
Descriptor | Insulin (2 entities in total) |
Functional Keywords | human insulin mutant, 35% cd3cn, monomer, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, pharmaceutical, secreted |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 6104.02 |
Authors | Bocian, W.,Kozerski, L. (deposition date: 2007-12-06, release date: 2008-10-28, Last modification date: 2022-03-16) |
Primary citation | Bocian, W.,Borowicz, P.,Sitkowski, J.,Tarnowska, A.,Bednarek, E.,Bogiel, M.,Kozerski, L. NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer Biopolymers, 89:820-830, 2008 Cited by PubMed: 18491415DOI: 10.1002/bip.21018 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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