2RN1

Liquid crystal solution structure of the kissing complex formed by the apical loop of the HIV TAR RNA and a high affinity RNA aptamer optimized by SELEX

2RN1 の概要

• エントリーDOI: 10.2210/pdb2rn1/pdb
• 関連するPDBエントリー: 1KIS
• NMR情報: BMRB: 11014
• 分子名称: RNA (5'-R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'), RNA (5'-R(P*GP*CP*UP*GP*GP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3') (2 entities in total)
• 機能のキーワード: rna kissing complex, hiv tar, high affinity rna aptamer selected by selex, liquid crystal nmr, ga base pair, rna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 10280.25

構造登録者

Van Melckebeke, H.,Devany, M.,Di Primo, C.,Beaurain, F.,Toulme, J.,Bryce, D.L.,Boisbouvier, J. (登録日: 2007-12-05, 公開日: 2008-09-23, 最終更新日: 2024-05-01)

• 主引用文献: Van Melckebeke, H.,Devany, M.,Di Primo, C.,Beaurain, F.,Bryce, D.L.,Boisbouvier, J.; Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex; Proc.Natl.Acad.Sci.Usa, 105:9210-9215, 2008; PubMed: 18607001; DOI: 10.1073/pnas.0712121105

実験手法

SOLUTION NMR