2RKB

Serine dehydratase like-1 from human cancer cells

2RKB の概要

• エントリーDOI: 10.2210/pdb2rkb/pdb
• 分子名称: Serine dehydratase-like, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: serine dehydratase, plp bound enzyme, enzyme found in human cancer cells, lyase, pyridoxal phosphate
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 169305.61

構造登録者

Yamada, T.,Komoto, J.,Kasuya, T.,Mori, H.,Ogawa, H.,Takusagawa, F. (登録日: 2007-10-16, 公開日: 2008-04-01, 最終更新日: 2017-10-25)

• 主引用文献: Yamada, T.,Komoto, J.,Kasuya, T.,Takata, Y.,Ogawa, H.,Mori, H.,Takusagawa, F.; A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: Crystal structure and site-directed mutagenesis studies.; Biochim.Biophys.Acta, 1780:809-818, 2008; PubMed: 18342636; DOI: 10.1016/j.bbagen.2008.01.020

実験手法

X-RAY DIFFRACTION (2.8 Å)