2RJ4

B-specific alpha-1,3-galactosyltransferase \ G176R +UDP+ADA

Summary for 2RJ4

Entry DOI	10.2210/pdb2rj4/pdb
Related	2RIT 2RIX 2RIY 2RIZ 2RJ0 2RJ1 2RJ5 2RJ6 2RJ7 2RJ8 2RJ9
Descriptor	Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	gtb abo rossman fold bbbb unliganded, blood group antigen, glycoprotein, glycosyltransferase, golgi apparatus, manganese, membrane, metal-binding, secreted, signal-anchor, transferase, transmembrane
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
Total number of polymer chains	1
Total formula weight	35266.32
Authors	Evans, S.V.,Alfaro, J.A. (deposition date: 2007-10-14, release date: 2008-02-05, Last modification date: 2024-02-21)
Primary citation	Alfaro, J.A.,Zheng, R.B.,Persson, M.,Letts, J.A.,Polakowski, R.,Bai, Y.,Borisova, S.N.,Seto, N.O.,Lowary, T.L.,Palcic, M.M.,Evans, S.V. ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283:10097-10108, 2008 Cited by PubMed: 18192272 DOI: 10.1074/jbc.M708669200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation