2RI3

Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358Q point mutation

2RI3 の概要

• エントリーDOI: 10.2210/pdb2ri3/pdb
• 関連するPDBエントリー: 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI5
• 分子名称: Lethal(3)malignant brain tumor-like protein, DI(HYDROXYETHYL)ETHER (3 entities in total)
• 機能のキーワード: beta barrel, alternative splicing, chromatin regulator, dna-binding, metal-binding, nucleus, repressor, transcription, transcription regulation, zinc, zinc-finger
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q9Y468
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36814.10

構造登録者

Li, H.,Patel, D.J. (登録日: 2007-10-10, 公開日: 2007-12-11, 最終更新日: 2023-11-15)

• 主引用文献: Li, H.,Fischle, W.,Wang, W.,Duncan, E.M.,Liang, L.,Murakami-Ishibe, S.,Allis, C.D.,Patel, D.J.; Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.; Mol.Cell, 28:677-691, 2007; PubMed: 18042461; DOI: 10.1016/j.molcel.2007.10.023

実験手法

X-RAY DIFFRACTION (2 Å)