2RHK
Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A
Summary for 2RHK
Entry DOI | 10.2210/pdb2rhk/pdb |
Related | 2D9N 2GX9 |
Descriptor | Non-structural protein 1, Cleavage and polyadenylation specificity factor subunit 4, NITRATE ION, ... (6 entities in total) |
Functional Keywords | influenza a, nonstructural protein, viral protein: host complex, zn finger, alternative splicing, cytoplasm, host-virus interaction, interferon antiviral system evasion, nucleus, rna-binding, suppressor of rna silencing, metal-binding, mrna processing, zinc, zinc-finger, metal binding protein, viral protein-metal binding protein complex, viral protein-nuclear protein complex, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, viral protein/nuclear protein |
Biological source | Influenza A Virus More |
Cellular location | Host nucleus: P03495 Nucleus: O95639 |
Total number of polymer chains | 4 |
Total formula weight | 49764.23 |
Authors | Das, K.,Ma, L.-C.,Xiao, R.,Radvansky, B.,Aramini, J.,Zhao, L.,Arnold, E.,Krug, R.M.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2007-10-09, release date: 2008-07-01, Last modification date: 2024-02-21) |
Primary citation | Das, K.,Ma, L.C.,Xiao, R.,Radvansky, B.,Aramini, J.,Zhao, L.,Marklund, J.,Kuo, R.L.,Twu, K.Y.,Arnold, E.,Krug, R.M.,Montelione, G.T. Structural basis for suppression of a host antiviral response by influenza A virus. Proc.Natl.Acad.Sci.Usa, 105:13093-13098, 2008 Cited by PubMed: 18725644DOI: 10.1073/pnas.0805213105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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