2RF5

Crystal structure of human tankyrase 1- catalytic PARP domain

2RF5 の概要

• エントリーDOI: 10.2210/pdb2rf5/pdb
• 分子名称: Tankyrase-1, ZINC ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: catalytic fragment, parp, structural genomics, structural genomics consortium, sgc, adp-ribosylation, ank repeat, chromosomal protein, glycosyltransferase, golgi apparatus, membrane, mrna transport, nad, nuclear pore complex, nucleus, phosphorylation, protein transport, telomere, transferase, translocation, transport
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: O95271
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29574.58

構造登録者

Lehtio, L.,Karlberg, T.,Arrowsmith, C.H.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Kotenyova, T.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Tresaugues, L.,van den Berg, S.,Welin, M.,Weigelt, J.,Structural Genomics Consortium (SGC) (登録日: 2007-09-28, 公開日: 2007-10-09, 最終更新日: 2023-08-30)

• 主引用文献: Lehtio, L.,Collins, R.,van den Berg, S.,Johansson, A.,Dahlgren, L.G.,Hammarstrom, M.,Helleday, T.,Holmberg-Schiavone, L.,Karlberg, T.,Weigelt, J.; Zinc binding catalytic domain of human tankyrase 1.; J.Mol.Biol., 379:136-145, 2008; PubMed: 18436240; DOI: 10.1016/j.jmb.2008.03.058

実験手法

X-RAY DIFFRACTION (2.3 Å)