2R92

Elongation complex of RNA polymerase II with artificial RdRP scaffold

Summary for 2R92

• Entry DOI: 10.2210/pdb2r92/pdb
• Related: 2R93
• Descriptor: RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'), DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, ... (16 entities in total)
• Functional Keywords: transferase/dna/rna, dna-binding, phosphorylation, rna polymerase ii, metal-binding, nuclear protein, transcription bubble, elongation complex, transferase, transcription, rna-dependent, rna-dependent rna synthesis, rdrp, ddrp, rna-binding, dna-directed rna polymerase, magnesium, nucleotidyltransferase, nucleus, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna damage, dna repair, mrna processing, transferase-rna complex, transferase/rna
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Nucleus : P20436 P38902 P04050 P08518 P16370 P20433 P20434 P34087; Nucleus, nucleolus : P27999 P22139 P40422; Cytoplasm : P20435
• Total number of polymer chains: 14
• Total formula weight: 525253.22

Authors

Lehmann, E.,Brueckner, F.,Cramer, P. (deposition date: 2007-09-12, release date: 2007-11-27, Last modification date: 2017-10-25)

• Primary citation: Lehmann, E.,Brueckner, F.,Cramer, P.; Molecular basis of RNA-dependent RNA polymerase II activity.; Nature, 450:445-449, 2007; PubMed: 18004386; DOI: 10.1038/nature06290

Experimental method

X-RAY DIFFRACTION (3.8 Å)