2R92

Elongation complex of RNA polymerase II with artificial RdRP scaffold

2R92 の概要

• エントリーDOI: 10.2210/pdb2r92/pdb
• 関連するPDBエントリー: 2R93
• 分子名称: RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'), DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, ... (16 entities in total)
• 機能のキーワード: transferase/dna/rna, dna-binding, phosphorylation, rna polymerase ii, metal-binding, nuclear protein, transcription bubble, elongation complex, transferase, transcription, rna-dependent, rna-dependent rna synthesis, rdrp, ddrp, rna-binding, dna-directed rna polymerase, magnesium, nucleotidyltransferase, nucleus, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna damage, dna repair, mrna processing, transferase-rna complex, transferase/rna
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• 細胞内の位置: Nucleus : P20436 P38902 P04050 P08518 P16370 P20433 P20434 P34087; Nucleus, nucleolus : P27999 P22139 P40422; Cytoplasm : P20435
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 525253.22

構造登録者

Lehmann, E.,Brueckner, F.,Cramer, P. (登録日: 2007-09-12, 公開日: 2007-11-27, 最終更新日: 2017-10-25)

• 主引用文献: Lehmann, E.,Brueckner, F.,Cramer, P.; Molecular basis of RNA-dependent RNA polymerase II activity.; Nature, 450:445-449, 2007; PubMed: 18004386; DOI: 10.1038/nature06290

実験手法

X-RAY DIFFRACTION (3.8 Å)