2R6P

Fit of E protein and Fab 1A1D-2 into 24 angstrom resolution cryoEM map of Fab complexed with dengue 2 virus.

2R6P の概要

• エントリーDOI: 10.2210/pdb2r6p/pdb
• EMDBエントリー: 1418
• 分子名称: Major envelope protein E, Heavy chain of 1A1D-2, Light chain of 1A1D-2 (3 entities in total)
• 機能のキーワード: fab, dengue, virus, neutralization, virus-immune system complex, icosahedral virus, virus/immune system
• 由来する生物種: Dengue virus 2 Puerto Rico/PR159-S1/1969; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 221965.94

構造登録者

Lok, S.M.,Kostyuchenko, V.K.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Rossmann, M.G. (登録日: 2007-09-06, 公開日: 2007-12-25, 最終更新日: 2024-02-21)

• 主引用文献: Lok, S.M.,Kostyuchenko, V.,Nybakken, G.E.,Holdaway, H.A.,Battisti, A.J.,Sukupolvi-Petty, S.,Sedlak, D.,Fremont, D.H.,Chipman, P.R.,Roehrig, J.T.,Diamond, M.S.,Kuhn, R.J.,Rossmann, M.G.; Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.; Nat.Struct.Mol.Biol., 15:312-317, 2008; PubMed: 18264114; DOI: 10.1038/nsmb.1382

実験手法

ELECTRON MICROSCOPY (24 Å)