2R5Q

Crystal Structure Analysis of HIV-1 Subtype C Protease Complexed with Nelfinavir

2R5Q の概要

• エントリーDOI: 10.2210/pdb2r5q/pdb
• 関連するPDBエントリー: 2R5P
• 分子名称: Protease, 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE (3 entities in total)
• 機能のキーワード: hiv-1 subtype c, aspartyl protease, hydrolase, protease, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 44142.71

構造登録者

Coman, R.M.,Robbins, A.H.,McKenna, R.,Dunn, B.M. (登録日: 2007-09-04, 公開日: 2007-11-20, 最終更新日: 2024-02-21)

• 主引用文献: Coman, R.M.,Robbins, A.H.,Fernandez, M.A.,Gilliland, C.T.,Sochet, A.A.,Goodenow, M.M.,McKenna, R.,Dunn, B.M.; The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease; Biochemistry, 47:731-743, 2008; PubMed: 18092815; DOI: 10.1021/bi7018332

実験手法

X-RAY DIFFRACTION (2.3 Å)