2R5M

Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in complex with peptide R-(me)K-S

2R5M の概要

• エントリーDOI: 10.2210/pdb2r5m/pdb
• 関連するPDBエントリー: 2R57 2R58 2R5A
• 分子名称: Polycomb protein Scm, peptide R(me)KS (3 entities in total)
• 機能のキーワード: mbt repeat, polycomb, sex comb on midleg, chromatin regulator, developmental protein, metal-binding, nucleus, repressor, transcription, transcription regulation
• 由来する生物種: Drosophila melanogaster (fruit fly); 詳細
• 細胞内の位置: Nucleus (Probable): Q9VHA0
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29802.79

構造登録者

Grimm, C.,Steuerwald, U.,Mueller, C.W. (登録日: 2007-09-04, 公開日: 2007-10-30, 最終更新日: 2021-10-20)

• 主引用文献: Grimm, C.,de Ayala Alonso, A.G.,Rybin, V.,Steuerwald, U.,Ly-Hartig, N.,Fischle, W.,Muller, J.,Muller, C.W.; Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.; Embo Rep., 8:1031-1037, 2007; PubMed: 17932512; DOI: 10.1038/sj.embor.7401085

実験手法

X-RAY DIFFRACTION (2.65 Å)