2R3Y

Crystal structure of the DegS protease in complex with the YWF activating peptide

Summary for 2R3Y

Entry DOI	10.2210/pdb2r3y/pdb
Related	1sot 1soz 1vcw 2r3u
Descriptor	Protease degS, Synthetic peptide YWF (3 entities in total)
Functional Keywords	reversible activation of a protease, catalytic triad, hydrolase, periplasm, serine protease, hydrolase-hydrolase activator complex, hydrolase/hydrolase activator
Biological source	Escherichia coli More
Cellular location	Periplasm (Potential): P0AEE3
Total number of polymer chains	6
Total formula weight	103581.36
Authors	Clausen, T.,Hasselblatt, H. (deposition date: 2007-08-30, release date: 2007-11-27, Last modification date: 2023-08-30)
Primary citation	Hasselblatt, H.,Kurzbauer, R.,Wilken, C.,Krojer, T.,Sawa, J.,Kurt, J.,Kirk, R.,Hasenbein, S.,Ehrmann, M.,Clausen, T. Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev., 21:2659-2670, 2007 Cited by PubMed: 17938245 DOI: 10.1101/gad.445307 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation