2R2R

d(ATTAGTTATAACTAAT) complexed with MMLV RT catalytic fragment

2R2R の概要

• エントリーDOI: 10.2210/pdb2r2r/pdb
• 関連するPDBエントリー: 2R2S 2R2T 2R2U
• 分子名称: DNA (5'-D(*DAP*DTP*DTP*DAP*DGP*DTP*DTP*DA)-3'), DNA (5'-D(P*DTP*DAP*DAP*DCP*DTP*DAP*DAP*DT)-3'), Reverse transcriptase, ... (4 entities in total)
• 機能のキーワード: bleomycin, drug-dna complex, protein-dna complex, mmlv rt, aspartyl protease, dna recombination, endonuclease, multifunctional enzyme, nuclease, nucleotidyltransferase, rna-directed dna polymerase, transferase-dna complex, transferase/dna
• 由来する生物種: Moloney murine leukemia virus (MoMLV)
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p15: Virion . Capsid protein p30: Virion . Nucleocapsid protein p10: Virion : P03355
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 33784.56

構造登録者

Goodwin, K.D.,Lewis, M.A.,Long, E.C.,Georgiadis, M.M. (登録日: 2007-08-27, 公開日: 2008-07-22, 最終更新日: 2024-02-21)

• 主引用文献: Goodwin, K.D.,Lewis, M.A.,Long, E.C.,Georgiadis, M.M.; Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.; Proc.Natl.Acad.Sci.Usa, 105:5052-5056, 2008; PubMed: 18362349; DOI: 10.1073/pnas.0708143105

実験手法

X-RAY DIFFRACTION (2.1 Å)