2R0N

The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate

2R0N の概要

• エントリーDOI: 10.2210/pdb2r0n/pdb
• 関連するPDBエントリー: 2R0M
• 分子名称: Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, 3-thiaglutaryl-CoA, ... (4 entities in total)
• 機能のキーワード: glutaryl-coa dehydrogenase, flavoprotein, isomerase, alternative splicing, disease mutation, fad, mitochondrion, oxidoreductase, polymorphism, transit peptide
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: Q92947
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45201.93

構造登録者

Rao, K.S.,Albro, M.,Fu, Z.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E. (登録日: 2007-08-20, 公開日: 2008-04-22, 最終更新日: 2023-08-30)

• 主引用文献: Rao, K.S.,Fu, Z.,Albro, M.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E.; The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.; Biochemistry, 46:14468-14477, 2007; PubMed: 18020372; DOI: 10.1021/bi7009597

実験手法

X-RAY DIFFRACTION (2.3 Å)