2R0M
The effect of a Glu370Asp Mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate
Summary for 2R0M
Entry DOI | 10.2210/pdb2r0m/pdb |
Related | 2r0n |
Descriptor | Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, 4-nitrobutanoic acid, ... (4 entities in total) |
Functional Keywords | glutaryl-coa dehydrogenase, flavoprotein, isomerase, alternative splicing, disease mutation, fad, mitochondrion, oxidoreductase, polymorphism, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: Q92947 |
Total number of polymer chains | 1 |
Total formula weight | 44421.33 |
Authors | Rao, K.S.,Fu, Z.,Albro, M.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E. (deposition date: 2007-08-20, release date: 2008-04-22, Last modification date: 2023-08-30) |
Primary citation | Rao, K.S.,Fu, Z.,Albro, M.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E. The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate. Biochemistry, 46:14468-14477, 2007 Cited by PubMed: 18020372DOI: 10.1021/bi7009597 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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