2QXG
Crystal Structure of Human Kallikrein 7 in Complex with Ala-Ala-Phe-chloromethylketone
Summary for 2QXG
Entry DOI | 10.2210/pdb2qxg/pdb |
Related | 2QXH 2QXI 2QXJ |
Descriptor | Kallikrein-7, L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide (3 entities in total) |
Functional Keywords | dimer, 37 loop, active site inhibitor, chloromethyl ketone, alternative splicing, glycoprotein, hydrolase, protease, secreted, serine protease, zymogen |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P49862 |
Total number of polymer chains | 2 |
Total formula weight | 49577.10 |
Authors | Debela, M.,Hess, P.,Magdolen, V.,Bode, W.,Steiner, T.,Goettig, P. (deposition date: 2007-08-11, release date: 2008-01-08, Last modification date: 2023-08-30) |
Primary citation | Debela, M.,Hess, P.,Magdolen, V.,Schechter, N.M.,Steiner, T.,Huber, R.,Bode, W.,Goettig, P. Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104:16086-16091, 2007 Cited by PubMed: 17909180DOI: 10.1073/pnas.0707811104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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