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2QXG

Crystal Structure of Human Kallikrein 7 in Complex with Ala-Ala-Phe-chloromethylketone

Summary for 2QXG
Entry DOI10.2210/pdb2qxg/pdb
Related2QXH 2QXI 2QXJ
DescriptorKallikrein-7, L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide (3 entities in total)
Functional Keywordsdimer, 37 loop, active site inhibitor, chloromethyl ketone, alternative splicing, glycoprotein, hydrolase, protease, secreted, serine protease, zymogen
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P49862
Total number of polymer chains2
Total formula weight49577.10
Authors
Debela, M.,Hess, P.,Magdolen, V.,Bode, W.,Steiner, T.,Goettig, P. (deposition date: 2007-08-11, release date: 2008-01-08, Last modification date: 2023-08-30)
Primary citationDebela, M.,Hess, P.,Magdolen, V.,Schechter, N.M.,Steiner, T.,Huber, R.,Bode, W.,Goettig, P.
Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104:16086-16091, 2007
Cited by
PubMed: 17909180
DOI: 10.1073/pnas.0707811104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

数据于2024-03-27公开中

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