2QV2

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

Summary for 2QV2

Entry DOI	10.2210/pdb2qv2/pdb
Descriptor	Inositol polyphosphate 5-phosphatase OCRL-1 (2 entities in total)
Functional Keywords	endocytosis, clathrin, appl1, phosphoinositide, ash, rhogap, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasmic vesicle, phagosome membrane (By similarity): Q01968
Total number of polymer chains	1
Total formula weight	39470.23
Authors	Mao, Y.,Erdman, K.S.,McCrea, H.J.,De Camilli, P. (deposition date: 2007-08-07, release date: 2007-08-21, Last modification date: 2024-02-21)
Primary citation	Erdmann, K.S.,Mao, Y.,McCrea, H.J.,Zoncu, R.,Lee, S.,Paradise, S.,Modregger, J.,Biemesderfer, D.,Toomre, D.,De Camilli, P. A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway Dev.Cell, 13:377-390, 2007 Cited by PubMed: 17765681 DOI: 10.1016/j.devcel.2007.08.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation