2QV2
A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway
Summary for 2QV2
Entry DOI | 10.2210/pdb2qv2/pdb |
Descriptor | Inositol polyphosphate 5-phosphatase OCRL-1 (2 entities in total) |
Functional Keywords | endocytosis, clathrin, appl1, phosphoinositide, ash, rhogap, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasmic vesicle, phagosome membrane (By similarity): Q01968 |
Total number of polymer chains | 1 |
Total formula weight | 39470.23 |
Authors | Mao, Y.,Erdman, K.S.,McCrea, H.J.,De Camilli, P. (deposition date: 2007-08-07, release date: 2007-08-21, Last modification date: 2024-02-21) |
Primary citation | Erdmann, K.S.,Mao, Y.,McCrea, H.J.,Zoncu, R.,Lee, S.,Paradise, S.,Modregger, J.,Biemesderfer, D.,Toomre, D.,De Camilli, P. A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway Dev.Cell, 13:377-390, 2007 Cited by PubMed: 17765681DOI: 10.1016/j.devcel.2007.08.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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