2QSC
Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide
Summary for 2QSC
Entry DOI | 10.2210/pdb2qsc/pdb |
Descriptor | Fab F425-B4e8, Light chain, Fab F425-B4e8, Heavy chain, Envelope glycoprotein gp120, ... (7 entities in total) |
Functional Keywords | fab-peptide complex, hiv-1, gp120, v3 loop, immunoglobulin fold, aids, apoptosis, envelope protein, fusion protein, glycoprotein, host-virus interaction, membrane, transmembrane, viral immunoevasion, virion, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 49822.08 |
Authors | Bell, C.H.,Schiefner, A.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2007-07-30, release date: 2008-01-15, Last modification date: 2020-07-29) |
Primary citation | Bell, C.H.,Pantophlet, R.,Schiefner, A.,Cavacini, L.A.,Stanfield, R.L.,Burton, D.R.,Wilson, I.A. Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J.Mol.Biol., 375:969-978, 2008 Cited by PubMed: 18068724DOI: 10.1016/j.jmb.2007.11.013 PDB entries with the same primary citation |
Experimental method |
Structure validation
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