2QR0
Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs
Summary for 2QR0
Entry DOI | 10.2210/pdb2qr0/pdb |
Descriptor | Fab-Fragment Light Chain, Fab-Fragment Heavy Chain, Vascular endothelial growth factor A (3 entities in total) |
Functional Keywords | vegf; antibody recognition; specificity; phage display, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted : P15692 |
Total number of polymer chains | 24 |
Total formula weight | 465857.59 |
Authors | Wiesmann, C. (deposition date: 2007-07-27, release date: 2007-08-14, Last modification date: 2017-10-25) |
Primary citation | Fellouse, F.A.,Esaki, K.,Birtalan, S.,Raptis, D.,Cancasci, V.J.,Koide, A.,Jhurani, P.,Vasser, M.,Wiesmann, C.,Kossiakoff, A.A.,Koide, S.,Sidhu, S.S. High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries J.Mol.Biol., 373:924-940, 2007 Cited by PubMed: 17825836DOI: 10.1016/j.jmb.2007.08.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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