2QPY

AR LBD with small molecule

2QPY の概要

• エントリーDOI: 10.2210/pdb2qpy/pdb
• 分子名称: Androgen receptor, Coactivator peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (5 entities in total)
• 機能のキーワード: androgen receptor dht coactivator, dna-binding, lipid-binding, metal-binding, nucleus, steroid-binding, transcription, transcription regulation, ubl conjugation, zinc, zinc-finger, dna binding protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Nucleus : P19091
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31455.17

構造登録者

Estebanez-Perpina, E.,Fletterick, R. (登録日: 2007-07-25, 公開日: 2007-09-25, 最終更新日: 2024-02-21)

• 主引用文献: Estebanez-Perpina, E.,Arnold, L.A.,Arnold, A.A.,Nguyen, P.,Rodrigues, E.D.,Mar, E.,Bateman, R.,Pallai, P.,Shokat, K.M.,Baxter, J.D.,Guy, R.K.,Webb, P.,Fletterick, R.J.; A surface on the androgen receptor that allosterically regulates coactivator binding.; Proc.Natl.Acad.Sci.Usa, 104:16074-16079, 2007; PubMed: 17911242; DOI: 10.1073/pnas.0708036104

実験手法

X-RAY DIFFRACTION (2.5 Å)