2QMK

Human pancreatic alpha-amylase complexed with nitrite

2QMK の概要

• エントリーDOI: 10.2210/pdb2qmk/pdb
• 関連するPDBエントリー: 1BSI 1CPU 1HNY
• 分子名称: Pancreatic alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: amylase, pichia pastoris, diabetes, catalysis, pancreatic, enzyme, human, hydrolase, anion activation, nitrite, chloride, carbohydrate metabolism, glycoprotein, glycosidase, metal-binding, pyrrolidone carboxylic acid, secreted
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56238.60

構造登録者

Williams, L.K.,Maurus, R.,Brayer, G.D. (登録日: 2007-07-16, 公開日: 2008-03-25, 最終更新日: 2023-08-30)

• 主引用文献: Maurus, R.,Begum, A.,Williams, L.K.,Fredriksen, J.R.,Zhang, R.,Withers, S.G.,Brayer, G.D.; Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity; Biochemistry, 47:3332-3344, 2008; PubMed: 18284212; DOI: 10.1021/bi701652t

実験手法

X-RAY DIFFRACTION (2.3 Å)