2QFG

Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H.

Summary for 2QFG

• Entry DOI: 10.2210/pdb2qfg/pdb
• Related: 1haq 2QFH
• Descriptor: Complement factor H (1 entity in total)
• Functional Keywords: x-ray scattering, complement, scr domain, factor h, age-related macular degeneration, complement alternate pathway, disease mutation, glycoprotein, immune response, innate immunity, sushi, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P08603
• Total number of polymer chains: 1
• Total formula weight: 35434.67

Authors

Okemefuna, A.I.,Gilbert, H.E.,Griggs, K.M.,Ormsby, R.J.,Gordon, D.L.,Perkins, S.J. (deposition date: 2007-06-27, release date: 2007-09-25, Last modification date: 2024-02-21)

• Primary citation: Okemefuna, A.I.,Gilbert, H.E.,Griggs, K.M.,Ormsby, R.J.,Gordon, D.L.,Perkins, S.J.; The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.; J.Mol.Biol., 375:80-101, 2008; PubMed: 18005991; DOI: 10.1016/j.jmb.2007.09.026

Experimental method

SOLUTION SCATTERING