2QDJ

Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture

Summary for 2QDJ

Entry DOI	10.2210/pdb2qdj/pdb
Descriptor	Retinoblastoma-associated protein (2 entities in total)
Functional Keywords	cyclin fold, cyclin wedge, antitumor protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P06400
Total number of polymer chains	1
Total formula weight	35427.97
Authors	Hassler, M.,Mittnacht, S.,Pearl, L.H. (deposition date: 2007-06-21, release date: 2008-01-22, Last modification date: 2011-07-13)
Primary citation	Hassler, M.,Singh, S.,Yue, W.W.,Luczynski, M.,Lakbir, R.,Sanchez-Sanchez, F.,Bader, T.,Pearl, L.H.,Mittnacht, S. Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol.Cell, 28:371-385, 2007 Cited by PubMed: 17996702 DOI: 10.1016/j.molcel.2007.08.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation