2QC6

Protein kinase CK2 in complex with DBC

2QC6 の概要

• エントリーDOI: 10.2210/pdb2qc6/pdb
• 分子名称: Casein kinase II subunit alpha, 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE (3 entities in total)
• 機能のキーワード: ck2, dbc, kinase inhibitors, coumarins, transferase
• 由来する生物種: Zea mays
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39641.13

構造登録者

Battistutta, R. (登録日: 2007-06-19, 公開日: 2008-02-26, 最終更新日: 2011-07-13)

• 主引用文献: Chilin, A.,Battistutta, R.,Bortolato, A.,Cozza, G.,Zanatta, S.,Poletto, G.,Mazzorana, M.,Zagotto, G.,Uriarte, E.,Guiotto, A.,Pinna, L.A.,Meggio, F.,Moro, S.; Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.; J.Med.Chem., 51:752-759, 2008; PubMed: 18251491; DOI: 10.1021/jm070909t

実験手法

X-RAY DIFFRACTION (1.85 Å)