EphB2/SNEW Antagonistic Peptide Complex

Summary for 2QBX

Related1NUK 1KGY 2BBA
DescriptorEphrin type-B receptor 2, antagonistic peptide, SULFATE ION, ... (4 entities in total)
Functional Keywordsreceptor tyrosine kinase, bi-directional signaling, tumorigenesis, angiogenesis, signaling protein, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P29323
Total number of polymer chains4
Total molecular weight51495.56
Chrencik, J.E.,Brooun, A.,Recht, M.I.,Nicola, G.,Pasquale, E.B.,Kuhn, P.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) (deposition date: 2007-06-18, release date: 2007-11-06, Last modification date: 2011-07-13)
Primary citation
Chrencik, J.E.,Brooun, A.,Recht, M.I.,Nicola, G.,Davis, L.K.,Abagyan, R.,Widmer, H.,Pasquale, E.B.,Kuhn, P.
Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.
J.Biol.Chem., 282:36505-36513, 2007
PubMed: 17897949 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M706340200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27770.3%8.1%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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