2QB5

Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-Kinase (ITPK1) in Complex with ADP and Mn2+

2QB5 の概要

• エントリーDOI: 10.2210/pdb2qb5/pdb
• 分子名称: Inositol-tetrakisphosphate 1-kinase, SULFATE ION, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: inositol, inositol kinase, kinase, itpk1, inositol 1, 3, 4-5/6-kinase, phosphate, inositol phosphate, inositolphosphate, polyphosphate, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80552.00

構造登録者

Chamberlain, P.P.,Lesley, S.A.,Spraggon, G. (登録日: 2007-06-15, 公開日: 2007-07-03, 最終更新日: 2024-02-21)

• 主引用文献: Chamberlain, P.P.,Qian, X.,Stiles, A.R.,Cho, J.,Jones, D.H.,Lesley, S.A.,Grabau, E.A.,Shears, S.B.,Spraggon, G.; Integration of inositol phosphate signaling pathways via human ITPK1.; J.Biol.Chem., 282:28117-28125, 2007; PubMed: 17616525; DOI: 10.1074/jbc.M703121200

実験手法

X-RAY DIFFRACTION (1.8 Å)