2QAF
Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP
Summary for 2QAF
Entry DOI | 10.2210/pdb2qaf/pdb |
Related | 2Q8L 2Q8Z |
Descriptor | Orotidine 5' monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | plasmodium falciparum, orotidine 5'-phosphate decarboxylase, covalently, 6-iodo-ump, lyase |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 2 |
Total formula weight | 80543.34 |
Authors | Liu, Y.,Lau, W.,Bello, A.M.,Kotra, L.P.,Hui, R.,Pai, E.F. (deposition date: 2007-06-15, release date: 2008-04-29, Last modification date: 2023-08-30) |
Primary citation | Bello, A.M.,Poduch, E.,Liu, Y.,Wei, L.,Crandall, I.,Wang, X.,Dyanand, C.,Kain, K.C.,Pai, E.F.,Kotra, L.P. Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase J.Med.Chem., 51:439-448, 2008 Cited by PubMed: 18189347DOI: 10.1021/jm7010673 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report