2QAD

Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4

2QAD の概要

• エントリーDOI: 10.2210/pdb2qad/pdb
• 分子名称: Envelope glycoprotein gp160, T-cell surface glycoprotein CD4, anti-HIV-1 antibody 412d light chain, ... (7 entities in total)
• 機能のキーワード: viral protein/immune system, viral protein-immune system complex
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 216737.58

構造登録者

Huang, C.-C.,Tang, M.,Robinson, J.,Wyatt, R.,Kwong, P.D. (登録日: 2007-06-14, 公開日: 2007-09-25, 最終更新日: 2023-11-15)

• 主引用文献: Huang, C.-C.,Lam, S.N.,Acharya, P.,Tang, M.,Xiang, S.-H.,Hussan, S.S.,Stanfield, R.L.,Robinson, J.,Sodroski, J.,Wilson, I.A.,Wyatt, R.,Bewley, C.A.,Kwong, P.D.; Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4; Science, 317:1930-1934, 2007; PubMed: 17901336; DOI: 10.1126/science.1145373

実験手法

X-RAY DIFFRACTION (3.3 Å)