2Q99

Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae

Summary for 2Q99

Entry DOI	10.2210/pdb2q99/pdb
Descriptor	Saccharopine dehydrogenase [NAD+, L-lysine-forming (2 entities in total)
Functional Keywords	dehydrogenase, alpha-aminoadipate pathway, fungal lysine synthesis, alpha/beta protein, rossmann fold, oxidoreductase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Cytoplasm : P38998
Total number of polymer chains	1
Total formula weight	42317.17
Authors	Berghuis, A.M.,Burk, D.L. (deposition date: 2007-06-12, release date: 2007-11-06, Last modification date: 2017-10-18)
Primary citation	Burk, D.L.,Hwang, J.,Kwok, E.,Marrone, L.,Goodfellow, V.,Dmitrienko, G.I.,Berghuis, A.M. Structural Studies of the Final Enzyme in the alpha-Aminoadipate Pathway-Saccharopine Dehydrogenase from Saccharomyces cerevisiae J.Mol.Biol., 373:745-754, 2007 Cited by PubMed: 17854830 DOI: 10.1016/j.jmb.2007.08.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation