2Q7L

The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and a TIF2 box3 Coactivator Peptide 740-753

Summary for 2Q7L

• Entry DOI: 10.2210/pdb2q7l/pdb
• Descriptor: Androgen receptor, Nuclear receptor coactivator 2, TESTOSTERONE, ... (5 entities in total)
• Functional Keywords: androgen receptor prostate cancer mutant h874y ligand binding domain, testosterone, tif2 boxiii coactivator peptide, hormone
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P10275 Q15596
• Total number of polymer chains: 2
• Total formula weight: 32121.57

Authors

Gampe, R.T. (deposition date: 2007-06-07, release date: 2007-07-24, Last modification date: 2024-02-21)

• Primary citation: Askew, E.B.,Gampe, R.T.,Stanley, T.B.,Faggart, J.L.,Wilson, E.M.; Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.; J.Biol.Chem., 282:25801-25816, 2007; PubMed: 17591767; DOI: 10.1074/jbc.M703268200

Experimental method

X-RAY DIFFRACTION (1.92 Å)