2Q7H

Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate

Summary for 2Q7H

• Entry DOI: 10.2210/pdb2q7h/pdb
• Related: 2Q7E 2Q7G 2ZIM
• Descriptor: Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: pyrrolysyl-trna synthetase, pyrrolysine, ligase
• Biological source: Methanosarcina mazei
• Cellular location: Cytoplasm (By similarity): Q8PWY1
• Total number of polymer chains: 1
• Total formula weight: 34799.40

Authors

Kavran, J.M.,Steitz, T.A. (deposition date: 2007-06-06, release date: 2007-07-24, Last modification date: 2024-02-21)

• Primary citation: Kavran, J.M.,Gundllapalli, S.,O'donoghue, P.,Englert, M.,Soll, D.,Steitz, T.A.; Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.; Proc.Natl.Acad.Sci.Usa, 104:11268-11273, 2007; PubMed: 17592110; DOI: 10.1073/pnas.0704769104

Experimental method

X-RAY DIFFRACTION (2.1 Å)