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2Q5A

human Pin1 bound to L-PEPTIDE

Replaces:  2ITI
Summary for 2Q5A
Entry DOI10.2210/pdb2q5a/pdb
Related1pin 2itk
DescriptorPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Five residue peptide, 3,6,9,12,15,18-HEXAOXAICOSANE, ... (4 entities in total)
Functional Keywordsisomerase ww domain, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: Q13526
Total number of polymer chains2
Total formula weight19625.73
Authors
Noel, J.P.,Zhang, Y. (deposition date: 2007-05-31, release date: 2007-06-26, Last modification date: 2011-07-13)
Primary citationZhang, Y.,Daum, S.,Wildemann, D.,Zhou, X.Z.,Verdecia, M.A.,Bowman, M.E.,Lucke, C.,Hunter, T.,Lu, K.P.,Fischer, G.,Noel, J.P.
Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2:320-328, 2007
Cited by
PubMed: 17518432
DOI: 10.1021/cb7000044
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

218500

数据于2024-04-17公开中

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