2Q58
Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate
Replaces: 2HERSummary for 2Q58
Entry DOI | 10.2210/pdb2q58/pdb |
Descriptor | Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID, ... (4 entities in total) |
Functional Keywords | farnesyl diphosphate synthase, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Cryptosporidium parvum |
Total number of polymer chains | 2 |
Total formula weight | 86636.11 |
Authors | Chruszcz, M.,Artz, J.,Zheng, H.,Dong, A.,Dunford, J.,Lew, J.,Zhao, Y.,Kozieradski, I.,Kavanaugh, K.L.,Opperman, U.,Sundstrom, M.,Weigelt, J.,Edwards, A.,Arrowsmith, C.,Bochkarev, A.,Hui, R.,Minor, W.,Structural Genomics Consortium (SGC) (deposition date: 2007-05-31, release date: 2007-06-12, Last modification date: 2023-08-30) |
Primary citation | Artz, J.D.,Dunford, J.E.,Arrowood, M.J.,Dong, A.,Chruszcz, M.,Kavanagh, K.L.,Minor, W.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R. Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis Chem.Biol., 15:1296-, 2008 Cited by PubMed: 19101474DOI: 10.1016/j.chembiol.2008.10.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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