2Q4R

Ensemble refinement of the protein crystal structure of human phosphomannomutase 2 (PMM2)

Summary for 2Q4R

Entry DOI	10.2210/pdb2q4r/pdb
Descriptor	Phosphomannomutase 2, 1,2-ETHANEDIOL, GLYCINE, ... (4 entities in total)
Functional Keywords	ensemble refinement, refinement methodology development, hs.459855, hs.313504, bc008310, phosphatase, pfam pf03332, had superfamily, jaecken disease, carbohydrate-deficient glycoprotein syndrome, structural genomics, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, isomerase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O15305
Total number of polymer chains	1
Total formula weight	28550.90
Authors	Levin, E.J.,Kondrashov, D.A.,Wesenberg, G.E.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2007-05-31, release date: 2007-06-19, Last modification date: 2023-11-15)
Primary citation	Levin, E.J.,Kondrashov, D.A.,Wesenberg, G.E.,Phillips, G.N. Ensemble refinement of protein crystal structures: validation and application. Structure, 15:1040-1052, 2007 Cited by PubMed: 17850744 DOI: 10.1016/j.str.2007.06.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation