2Q3D

2.2 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) From MYCOBACTERIUM TUBERCULOSIS in Complex with the Reaction Intermediate ALPHA-AMINOACRYLATE

Summary for 2Q3D

Entry DOI	10.2210/pdb2q3d/pdb
Related	2Q3B 2Q3C
Descriptor	Cysteine synthase A, 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	mycobacterium tuberculosis, pyridoxal-5'-phosphate, sulphur metabolism, cysteine biosynthesis, alpha-aminoacrylate intermediate, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	33506.30
Authors	Schneider, G.,Schnell, R. (deposition date: 2007-05-30, release date: 2007-06-12, Last modification date: 2023-08-30)
Primary citation	Schnell, R.,Oehlmann, W.,Singh, M.,Schneider, G. Structural Insights into Catalysis and Inhibition of O-Acetylserine Sulfhydrylase from Mycobacterium tuberculosis: CRYSTAL STRUCTURES OF THE ENZYME {alpha}-AMINOACRYLATE INTERMEDIATE AND AN ENZYME-INHIBITOR COMPLEX. J.Biol.Chem., 282:23473-23481, 2007 Cited by PubMed: 17567578 DOI: 10.1074/jbc.M703518200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation