2Q3C

2.1 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with the Inhibitory Peptide DFSI

2Q3C の概要

• エントリーDOI: 10.2210/pdb2q3c/pdb
• 関連するPDBエントリー: 2Q3B 2Q3D
• 分子名称: Cysteine synthase A, DFSI inhibitory peptide, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, pyridoxal-5'-phosphate, sulphur metabolism, cysteine biosynthesis, sat, peptide-inhibitor, transferase
• 由来する生物種: Mycobacterium tuberculosis; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33894.69

構造登録者

Schneider, G.,Schnell, R. (登録日: 2007-05-30, 公開日: 2007-06-12, 最終更新日: 2023-11-15)

• 主引用文献: Schnell, R.,Oehlmann, W.,Singh, M.,Schneider, G.; Structural Insights into Catalysis and Inhibition of O-Acetylserine Sulfhydrylase from Mycobacterium tuberculosis: CRYSTAL STRUCTURES OF THE ENZYME {alpha}-AMINOACRYLATE INTERMEDIATE AND AN ENZYME-INHIBITOR COMPLEX.; J.Biol.Chem., 282:23473-23481, 2007; PubMed: 17567578; DOI: 10.1074/jbc.M703518200

実験手法

X-RAY DIFFRACTION (2.1 Å)