2Q16

Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP

Summary for 2Q16

• Entry DOI: 10.2210/pdb2q16/pdb
• Related: 1K7K 2PYU
• Descriptor: HAM1 protein homolog, CALCIUM ION, SODIUM ION, ... (6 entities in total)
• Functional Keywords: itp pyrophosphatase x-ray structure enzyme mechanism substrate, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 48259.46

Authors

Singer, A.U.,Lam, R.,Proudfoot, M.,Skarina, T.,Savchenko, A.,Yakunin, A.F. (deposition date: 2007-05-23, release date: 2008-02-19, Last modification date: 2024-02-21)

• Primary citation: Savchenko, A.,Proudfoot, M.,Skarina, T.,Singer, A.,Litvinova, O.,Sanishvili, R.,Brown, G.,Chirgadze, N.,Yakunin, A.F.; Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.; J.Mol.Biol., 374:1091-1103, 2007; PubMed: 17976651; DOI: 10.1016/j.jmb.2007.10.012

Experimental method

X-RAY DIFFRACTION (1.95 Å)