2PWX
Crystal structure of G11A mutant of SARS-CoV 3C-like protease
2PWX の概要
エントリーDOI | 10.2210/pdb2pwx/pdb |
分子名称 | 3C-like proteinase (2 entities in total) |
機能のキーワード | chymotrypsin fold, hydrolase |
由来する生物種 | SARS coronavirus |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 34034.79 |
構造登録者 | |
主引用文献 | Chen, S.,Hu, T.,Zhang, J.,Chen, J.,Chen, K.,Ding, J.,Jiang, H.,Shen, X. Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations. J.Biol.Chem., 283:554-564, 2008 Cited by PubMed: 17977841DOI: 10.1074/jbc.M705240200 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.5 Å) |
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