2PWT
Crystal structure of the bacterial ribosomal decoding site complexed with aminoglycoside containing the L-HABA group
Summary for 2PWT
Entry DOI | 10.2210/pdb2pwt/pdb |
Descriptor | 22-mer of the ribosomal decoding site, DOUBLY FUNCTIONALIZED PAROMOMYCIN PM-II-162 (3 entities in total) |
Functional Keywords | aminoglycoside; haba group; ribosomal decoding site; x-ray analysis; rna, rna-antibiotic complex, rna/antibiotic |
Total number of polymer chains | 2 |
Total formula weight | 16078.00 |
Authors | Kondo, J.,Pachamuthu, K.,Francois, B.,Szychowski, J.,Hanessian, S.,Westhof, E. (deposition date: 2007-05-13, release date: 2007-09-18, Last modification date: 2024-03-13) |
Primary citation | Kondo, J.,Pachamuthu, K.,Francois, B.,Szychowski, J.,Hanessian, S.,Westhof, E. Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity Chemmedchem, 2:1631-1638, 2007 Cited by PubMed: 17722211DOI: 10.1002/cmdc.200700113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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