2PSX

Crystal Structure of Human Kallikrein 5 in complex with Leupeptin

Summary for 2PSX

• Entry DOI: 10.2210/pdb2psx/pdb
• Related: 2PSY
• Related PRD ID: PRD_000216
• Descriptor: Kallikrein-5, LEUPEPTIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: zinc inhibition, stratum corneum, glcosylation, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: Q9Y337
• Total number of polymer chains: 2
• Total formula weight: 26046.90

Authors

Debela, M.,Bode, W.,Goettig, P. (deposition date: 2007-05-07, release date: 2007-09-11, Last modification date: 2023-08-30)

• Primary citation: Debela, M.,Goettig, P.,Magdolen, V.,Huber, R.,Schechter, N.M.,Bode, W.; Structural basis of the zinc inhibition of human tissue kallikrein 5.; J.Mol.Biol., 373:1017-1031, 2007; PubMed: 17881000; DOI: 10.1016/j.jmb.2007.08.042

Experimental method

X-RAY DIFFRACTION (2.3 Å)