2PSU
Crystal Structure of wild type HIV-1 protease in complex with CARB-AD37
Summary for 2PSU
Entry DOI | 10.2210/pdb2psu/pdb |
Related | 2psv |
Descriptor | Protease, PHOSPHATE ION, ACETATE ION, ... (5 entities in total) |
Functional Keywords | drug design, hiv-1 protease, protease inhibitor, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22647.19 |
Authors | Schiffer, C.A.,Nalam, M.N.L. (deposition date: 2007-05-07, release date: 2007-06-05, Last modification date: 2023-08-30) |
Primary citation | Chellappan, S.,Kiran Kumar Reddy, G.S.,Ali, A.,Nalam, M.N.,Anjum, S.G.,Cao, H.,Kairys, V.,Fernandes, M.X.,Altman, M.D.,Tidor, B.,Rana, T.M.,Schiffer, C.A.,Gilson, M.K. Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis. Chem.Biol.Drug Des., 69:298-313, 2007 Cited by PubMed: 17539822DOI: 10.1111/j.1747-0285.2007.00514.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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