2PR0

Crystal structure of Sylvaticin, a new secreted protein from Pythium Sylvaticum

2PR0 の概要

• エントリーDOI: 10.2210/pdb2pr0/pdb
• 関連するPDBエントリー: 2POS
• 分子名称: sylvaticin, NICKEL (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: elicitin, toxin
• 由来する生物種: Pythium sylvaticum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 21183.73

構造登録者

Lascombe, M.B.,Prange, T.,Retailleau, P. (登録日: 2007-05-03, 公開日: 2008-03-18, 最終更新日: 2024-11-13)

主引用文献

Lascombe, M.B.,Retailleau, P.,Ponchet, M.,Industri, B.,Blein, J.P.,Prange, T.
Structure of sylvaticin, a new alpha-elicitin-like protein from Pythium sylvaticum.
Acta Crystallogr.,Sect.D, 63:1102-1108, 2007

PubMed Abstract: The structure of sylvaticin, a 10 kDa major pythin protein excreted by the parasitic oomycete Pythium sylvaticum, has been determined. Although closely related to alpha-elicitins in its biological response, toxicity and overall structure, sylvaticin presents a number of structural features that make it an unusual member of the elicitin class. Elicitins possess a large hydrophobic cavity and the mechanism of the systemic acquired resistance induced in planta is known to proceed through lipid transport and complexation within this cavity. Unlike other elicitins, sylvaticin contains tryptophan residues, one of which points inwards towards the central cavity, thus limiting access to sterols. In the case of sylvaticin, the sterol-transport mechanism is likely to be of less importance compared with other members of the elicitin family and still remains to be fully characterized.

PubMed: 17881828
DOI: 10.1107/S0907444907043363

実験手法

X-RAY DIFFRACTION (1.72 Å)